In this article, the author assesses the benefits and risks of studies that intentionally expose research subjects to environmental agents. He describes these types of studies, identify their benefits and risks, compare them to other research methods that can be used to investigate the relationship between environmental exposures and disease, and discuss some issues related to research design and risk minimization.
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RESNIK, DAVID B. 1; Email Address: resnikd@niehs.nih.gov; Affiliations: 1: National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA; Issue Info: Jan2007, Vol. 14 Issue 1, p35; Thesaurus Term: RESEARCH; Thesaurus Term: RISK exposure; Subject Term: GUINEA pigs; Subject Term: EVALUATION; Subject Term: ENVIRONMENTAL exposure; Subject Term: DISEASES; Subject Term: EXPERIMENTAL design; Author-Supplied Keyword: benefits; Author-Supplied Keyword: environment; Author-Supplied Keyword: Environmental Protection Agency; Author-Supplied Keyword: ethics; Author-Supplied Keyword: exposure studies; Author-Supplied Keyword: pesticides; Author-Supplied Keyword: regulation; Author-Supplied Keyword: risks; Number of Pages: 21p; Document Type: Article