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Single Subject Research Design

This bibliography focuses on how to design a research project that uses only one research subject, the ethics of research of this type, and examples of other single-subject research projects.

Backman, Catherine L., and Susan R. Harris. "Case Studies, Single-Subject Research, and N of 1 Randomized Trials. Comparisons and Contrasts." American Journal of Physical Medicine & Rehabilitation 78.2 (1999): 170-6.

Barlow, David H., Frank Andrasik, and Michael Hersen. Single Case Experimental Design Boston: Allyn and Bacon, 2007.

Beeson, Pélagie M. and Randall R. Robeyi. “Evaluating Single-Subject Treatment Research: Lessons Learned from the Aphasia Literature.” Neuropsychology Review 16.4 (December 2006): 161-169.

Blythe, Betty J. and Scott Briar. “Developing Empirically Based Models of Practice.” Social Work (Nov.-Dec. 1985): 483-88.

Bobrovitz, Candace D., and Kenneth J. Ottenbacher. "Comparison of Visual Inspection and Statistical Analysis of Single-Subject Data in Rehabilitation Research." Journal of Engineering and Applied Science 77.2 (1998): 94-102.

Bordens, Kenneth S., and Bruce B. Abbott. Research Design and Methods: A Process Approach. 2nd ed. Mountain View, Calif: Mayfield Pub. Co, 1991.

Brossart, Daniel F. et al. “The Relationship Between Visual Analysis and Five Statistical Analyses in a Simple AB Single-Case Research Design.” Behavior Modification 30.5 (September 2006): 531-563.

Cleland, Joshua, Gary c. Hunt, and Jessica Palmer. "Effectiveness of Neural Mobilization in the Treatment of a Patient with Lower Extremity Neurogenic Pain: A Single--Case Design." Journal of Manual & Manipulative Therapy 12.3 (2004): 143-52.

Davidson, Park Olof and Charles G. Costello. N=1: Experimental Studies of Single Cases; An Enduring Problem in Psychology. New York: Van Nostrand Reinhold Co., 1969.

Evers, Colin W. and Echo H. Wu. “On Generalizing from Single Case Studies: Epistemological Reflections.” Journal of Philosophy of Education 40.4 (November 2006): 511-526.

"Flexibility of Single-subject Experimental Designs. Part I: Review of the Basics of Single-subject Designs." The Journal of Speech and Hearing Disorders 51.3 (Aug. 1986): 194-203.

"Flexibility of Single-subject Experimental Designs. Part II: Design Selection and Arrangement of Experimental Phases." The Journal of Speech and Hearing Disorders 51.3 (Aug. 1986): 204-14.

"Flexibility of Single-subject Experimental Designs. Part III: Using Flexibility to Design or Modify Experiments." The Journal of Speech and Hearing Disorders 51.3 (Aug. 1986): 214-25.

Francis, N.A. “Single Subject Trials in Primary Care.” Postgraduate Medical Journal 81.959 (September 2005): 547-548.

Janosky, J. E. "Use of the Single Subject Design for Practice Based Primary Care Research." Postgraduate Medical Journal 81.959 (2005): 549-51.

Kazdin, Alan: Single-Case Research Designs. New York: Oxford University Press, 1982.

Krishef, Curtis H. Fundamental Approaches to Single Subject Design and Analysis. Malabar, FL: Krieger Pub. Co. 1991.

Magill, J. and L. Barton. "Single Subject Research Designs in Occupational Therapy Literature." Canadian Journal of Occupational Therapy 52.2 (April 1985): 53-8.

McReynolds, Leija and Kearns Kevin. Single-Subject Experimental Designs in Communicative Disorders Baltimore, Maryland: University Park Press, 1983.

Millard, Sharon K. “The Value of Single-Case Research.” International Journal of Language and Communication Disorders Vol. 33, Supplement (1998): 370-73.

Newcombe, R.G. “Should the Single Subject Design be Regarded as a Valid Alternative to the Randomized Controlled Trial?” Postgraduate Medical Journal 81.959 (September 2005): 546-547.

Palisano, Robert J. “The Case Report, Case Study, and Single Subject Design.” Physical and Occupational Therapy in Pediatrics 24.4 (2007): 1-5.

Parker, Richard, and Shanna Hagan-Burke. “Useful Effect Size Interpretations for Single Case Research.” Behavior Therapy 38.1 (March 2007): 95-105.

Pui-Wa, Maria Smith and Hoi K. Suen. “The Use of Generalizability Theory to Estimate Data Reliability in Single-Subject Observational Research.” Psychology in Schools 44.5 (May 2007): 433-439.

Richards, Stephen et al. Single Subject Research: Applications in Educational and Clinical Settings. San Diego: Singular Pub. Group, 1999.
[See esp. Ch. 4, "Issues in Single Subject Research", with a section on ethics.]

Scruggs T.E. and M.A.Mastropieri. "Summarizing Single-subject Research: Issues and Applications.” Behavior Modification. 22.3 (July 1998): 221-42.

Tankersley, M. et al. “Single Subject Research Methods in Rehabilitation.” Work 26.1 (2006): 85-92.

Thomas, Edwin J. "Research and Service in Single-case Experimentation: Conflicts and Choices.” Social Work Research and Abstracts 14.4 (1978): 20-31.

Thompson, C. K. "Single Subject Controlled Experiments in Aphasia: The Science and the State of the Science." Journal of Communication Disorders. 39.4 (2006): 266-91.

Tripodi, Tony: A Primer on Single-Subject Design for Clinical Social Workers. Washington, DC: National Association of Social Workers (NASW) Press, 1998.

Wakefield, Jerome C. and Stuart A. Kirk. "What the Practitioner Knows versus what the Client is Told: Neglected Dilemmas of Informed Consent in an account of Single-System Designs.” Journal of Social Work Education 33 (Spring/Summer 1997): 275-91.

Zhan, Su and Kenneth J. Ottenbacher. “Single-subject Research Design for Disability Research.” Disability and Rehabilitation 23.1 (2001): 1-8.


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