The Inclusion of Minority Groups in Clinical Trials: Problems of Under Representation and Under Reporting of Data

TitleThe Inclusion of Minority Groups in Clinical Trials: Problems of Under Representation and Under Reporting of Data
Publication TypeJournal Article
Year of Publication2004
AuthorsRochon, P, Mashari, A, Cohen, A, Misra, A, Laxer, D, Streiner, D, Clark, J, Dergal, J, Gold, JL
JournalAccountability in Research: Policies & Quality Assurance
Volume11
Issue3/4
Pagination215-223
Type of ArticleArticle
Publication Languageeng
ISSN Number08989621
Accession Number15902119
KeywordsClinical , ethnic , ETHNICITY , Human , key , Medical , MEDICINE , Minorities , MINORITY , research , systematic
AbstractIn order to evaluate the representation of minority groups in randomized control trials, and the frequency with which this information is reported, the researchers collected data about the racial/ethnic composition of study samples from all randomized control trials (RCTs) published in six leading medical journals in 1999. They found that of the 280 RCTs, most provided no information on the race/ethnicity of participants. Relative to other trials, those funded by the National Institute of Health were more likely to report race/ethnicity data and to include nonwhite participants. The researchers concluded that minority groups are currently under-represented in clinical trials, and that ethnicity and race of research participants is also underreported, though the NIH examples shows that mandatory reporting policies may have a positive effect on both reporting and representation.
NotesRochon, Paula 1; Email Address: paula.rochon@utoronto.ca; Mashari, Azad 2; Cohen, Ariel 2; Misra, Anjali 2; Laxer, Dara 2; Streiner, David 2; Clark, Jocalyn 3; Dergal, Julie 2; Gold, Jennifer 4; Affiliations: 1: Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Departments of Medicine and Public Health Sciences, University of Toronto, Institute for Clinical Evaluative Sciences; 2: Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ontario; 3: Department of Public Health Sciences and The Centre for Research in Women's Health, University of Toronto, Toronto, Ontario, Canada; 4: Faculty of Law, McGill University, Montreal, Quebec, Canada; Issue Info: Jul2004, Vol. 11 Issue 3/4, p215; Thesaurus Term: RESEARCH; Subject Term: MINORITIES; Subject Term: ETHNIC groups; Subject Term: CLINICAL medicine; Subject Term: CLINICAL trials; Subject Term: MEDICINE; Subject Term: HUMAN experimentation in medicine; Author-Supplied Keyword: clinical trials; Author-Supplied Keyword: ethnicity; Author-Supplied Keyword: Key words; Author-Supplied Keyword: medical journals; Author-Supplied Keyword: minority groups; Author-Supplied Keyword: systematic review; NAICS/Industry Codes: 541712 Reseach and Development in the Physical, Engineering, and Life Sciences (except Biotechnology); Number of Pages: 9p; Document Type: Article
DOI10.1080/08989620490891412
Short TitleThe Inclusion of Minority Groups in Clinical Trials: Problems of Under Representation and Under Reporting of Data
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