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The Antidepressant Debate and Ethically Defensible Placebo-Controlled Trials


By KBL781 - Posted on 28 September 2010

TitleThe Antidepressant Debate and Ethically Defensible Placebo-Controlled Trials
Publication TypeJournal Article
Year of Publication2008
AuthorsWaring, Duff R.
JournalIRB: Ethics & Human Research
Volume30
Issue6
Pagination12-16
Type of ArticleArticle
Publication Languageeng
ISSN Number01937758
Accession Number35618178
KeywordsANTIDEPRESSANTS , Clinical , Drugs , Medical , MEDICINE , Moral , Placebos , PSYCHOTROPIC , RANDOMIZED
Abstract

The article discusses the ethical issue involved in the argument concerning the utilization of placebo in conducting randomized clinical trials for antidepressant drugs. It states that the debate centers on the effectiveness and reliability of the drug to treat various diseases based on the clinical trials conducted. It reveals that placebo controls for drug trials are ethically defensible when the placebo plays essential role in assessing the drug's effectiveness.

Notes

Waring, Duff R.; Source Info: Nov/Dec2008, Vol. 30 Issue 6, p12; Subject Term: MEDICAL ethics; Subject Term: MEDICINE -- Research; Subject Term: PLACEBOS (Medicine); Subject Term: CLINICAL trials; Subject Term: ANTIDEPRESSANTS; Subject Term: PSYCHOTROPIC drugs; Subject Term: DRUGS -- Testing; Subject Term: MORAL & ethical aspects; Subject Term: RANDOMIZED controlled trials; Number of Pages: 5p; Document Type: Article

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