The Ethics of Single Blind Trials

TitleThe Ethics of Single Blind Trials
Publication TypeJournal Article
Year of Publication2005
AuthorsHeckerling, PS
JournalIRB: Ethics & Human Research
Volume27
Issue4
Pagination12-16
Type of ArticleArticle
Publication Languageeng
ISSN Number01937758
Accession Number17649205
KeywordsClinical , Medical , MEDICINE , Patients , Placebos , research
AbstractPresents an example of a single-blind trial similar to one encountered by our Institutional Review Board, to discuss some of the ethical issues that such a trial presents, and make recommendations for weighing the risks, benefits, and harms associated with single-blind trials. Definition of a single-blind trial as a study in which only the research subjects are blinded to treatment assignment; Unawareness of the research subjects of whether they are receiving the active intervention or placebo; Generation of scientifically valid knowledge to disturb equipoise and inform the treatment of future patients.
NotesHeckerling, Paul S. 1; Affiliation: 1: Chair, Biomedical-Behavioral Institutional Review Board, University of Illinois at Chicago, Chicago, IL; Source Info: Jul/Aug2005, Vol. 27 Issue 4, p12; Subject Term: MEDICAL ethics; Subject Term: RESEARCH; Subject Term: PLACEBOS (Medicine); Subject Term: MEDICINE & psychology; Subject Term: CLINICAL trials; Subject Term: PATIENTS; Number of Pages: 5p; Document Type: Article
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