Monitoring Reportable Events and Unanticipated Problems: The PHAROS and PREDICT Studies of Huntington Disease

TitleMonitoring Reportable Events and Unanticipated Problems: The PHAROS and PREDICT Studies of Huntington Disease
Publication TypeJournal Article
Year of Publication2007
AuthorsErwin, C, Hersch, S
JournalIRB: Ethics & Human Research
Volume29
Issue3
Pagination11-16
Type of ArticleArticle
Publication Languageeng
ISSN Number01937758
Accession Number25128640
KeywordsCommittees , Genetic , Human , HUNTINGTON'S , MEDICINE , research , United
AbstractThe article reports on the events and unanticipated problems faced during the two observational studies for Huntington disease in the U.S. These include the Prospective Huntington At Risk Observational Study (PHAROS) and the Neurobiological Predictors of Huntington Disease (PREDICT-HD) by the Huntington Study Group. The Event Monitoring Committee is responsible for identifying the risks during the studies including the possibility of physical harm and psychological, social and economic risks.
NotesErwin, Cheryl 1 Hersch, Steven 2; Affiliation: 1: Assistant Professor, Department of Family and Community Medicine, University of Texas Houston Medical School 2: Associate Professor, Mass General Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, MA; Source Info: May/Jun2007, Vol. 29 Issue 3, p11; Subject Term: MEDICINE -- Research; Subject Term: HUNTINGTON'S chorea; Subject Term: RESEARCH; Subject Term: HUMAN experimentation in medicine; Subject Term: GENETIC disorders; Subject Term: RESEARCH teams; Subject Term: COMMITTEES; Subject Term: UNITED States; NAICS/Industry Codes: 541712 Reseach and Development in the Physical, Engineering, and Life Sciences (except Biotechnology); Number of Pages: 6p; Document Type: Article
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