Ethical Issues in Field Trials of Genetically Modified Disease-Resistant Mosquitoes.

TitleEthical Issues in Field Trials of Genetically Modified Disease-Resistant Mosquitoes.
Publication TypeJournal Article
Year of Publication2014
AuthorsResnik, DB
JournalDeveloping World Bioethics
Pagination37 - 46
Date Published2014/04//
Publication Languageeng
ISBN Number14718731
KeywordsDeveloping , DISEASES , ENVIRONMENTAL , ethics , FIELD , GENETICALLY , Informed , MALARIA , MOSQUITOES , PUBLIC , Transgenic
AbstractMosquito-borne diseases take a tremendous toll on human populations, especially in developing nations. In the last decade, scientists have developed mosquitoes that have been genetically modified to prevent transmission of mosquito-borne diseases, and field trials have been conducted. Some mosquitoes have been rendered infertile, some have been equipped with a vaccine they transmit to humans, and some have been designed to resist diseases. This article focuses on ethical issues raised by field trials of disease-resistant, genetically modified mosquitoes.  To address this concern, field trials should take place only when the targeted disease is a significant public health problem in an isolated area, the benefits of the trial for the community are likely to outweigh the risks, community leaders approve of the trial, and there are measures in place to protect the welfare of un-enrolled community members, such as informing the community about the study and offering free treatment to people who contract mosquito-borne diseases. Since the justification of any field trial depends on a careful examination of the scientific and ethical issues, proposed studies should be evaluated on a case-by-case basis.
NotesAccession Number: 94914685; Resnik, David B.; Source Info: Apr2014, Vol. 14 Issue 1, p37; Subject Term: MOSQUITOES; Subject Term: TRANSGENIC organisms; Subject Term: PUBLIC health; Subject Term: ETHICS; Subject Term: DISEASES; Subject Term: DEVELOPING countries; Author-Supplied Keyword: environmental impacts; Author-Supplied Keyword: ethics; Author-Supplied Keyword: field trials; Author-Supplied Keyword: genetically modified mosquitoes; Author-Supplied Keyword: informed consent; Author-Supplied Keyword: malaria; Author-Supplied Keyword: public health; NAICS/Industry Codes: 525120 Health and Welfare Funds; Number of Pages: 10p; Document Type: Article
Short TitleDeveloping World Bioethics