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Professional Responsibility and Codes of Conduct presents an overview of major issues concerning professionalism as they relate to the Responsible Conduct of Research (RCR). Joe Herkert emphasizes both the micro (between individuals) and macro (between professionals and society) ethical dimensions of professional responsibility and codes of conduct. We compare ethical codes with aspects of moral theory, expanding the discussion with some of the classical readings for this topic. We present a case study from the Association for Practical and Professional Ethics. We consider the complex issue of whistle-blowing. We close with a sampling of additional resources.