<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><rec-number>7308</rec-number><ref-type>Case Study </ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yaich, Lauren</style></author></authors><translated-authors><author><style face="normal" font="default" size="100%">University of Pittsburgh at Bradford, Division of Biological and Health Sciences</style></author></translated-authors></contributors><titles><title><style face="normal" font="default" size="100%">Sonic Hedgehog : Genetic Abnormalities and Tissue Donations </style></title><short-title><style face="normal" font="default" size="100%">Sonic Hedgehog</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">BIOETHICS</style></keyword><keyword><style  face="normal" font="default" size="100%">BIOLOGY</style></keyword><keyword><style  face="normal" font="default" size="100%">BIRTH</style></keyword><keyword><style  face="normal" font="default" size="100%">BRAIN</style></keyword><keyword><style  face="normal" font="default" size="100%">cell</style></keyword><keyword><style  face="normal" font="default" size="100%">CONGENITAL</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyclops</style></keyword><keyword><style  face="normal" font="default" size="100%">GENETICS</style></keyword><keyword><style  face="normal" font="default" size="100%">Holoprosencephaly;</style></keyword><keyword><style  face="normal" font="default" size="100%">Medical</style></keyword><keyword><style  face="normal" font="default" size="100%">MEDICINE</style></keyword><keyword><style  face="normal" font="default" size="100%">neuroscience</style></keyword><keyword><style  face="normal" font="default" size="100%">Organ</style></keyword><keyword><style  face="normal" font="default" size="100%">Organ Donation and Transplantation</style></keyword><keyword><style  face="normal" font="default" size="100%">signal</style></keyword><keyword><style  face="normal" font="default" size="100%">TISSUE</style></keyword></keywords><taxonomies><taxonomy><style  face="normal" font="default" size="100%">Organ Donation and Transplantation</style></taxonomy><taxonomy><style  face="normal" font="default" size="100%">Bioethics</style></taxonomy><taxonomy><style  face="normal" font="default" size="100%">Neuroscience</style></taxonomy><taxonomy><style  face="normal" font="default" size="100%">Genetics</style></taxonomy><taxonomy><style  face="normal" font="default" size="100%">Medicine</style></taxonomy><taxonomy><style  face="normal" font="default" size="100%">Biology</style></taxonomy></taxonomies><pubtype><style  face="normal" font="default" size="100%">Case Study </style></pubtype><audience-level><style  face="normal" font="default" size="100%">ug</style></audience-level><dates><year><style  face="normal" font="default" size="100%">2001</style></year><pub-dates><date><style  face="normal" font="default" size="100%">04/2001</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://sciencecases.lib.buffalo.edu/cs/collection/detail.asp?case_id=380&id=380</style></url></web-urls></urls><publisher><style face="normal" font="default" size="100%">National Center for Case Study Teaching in Science, University at Buffalo</style></publisher><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">In this case study about a baby born with the genetic condition holoprosencephaly, students explore the “Sonic hedgehog” gene, signal transduction, and the ethics of body and tissue donation. The assignment involves students writing an informed consent document that explains the science behind this congenital abnormality. Designed for an upper-level undergraduate biology course, the case could also be used in a cell biology, developmental biology, neurobiology, or other related upper-level course.</style></abstract><notes><style face="normal" font="default" size="100%">Case from the National Center for Case Study Teaching in Science, University at Buffalo. http://sciencecases.lib.buffalo.edu/cs/</style></notes></record></records></xml>