Manufacturing Mistrust: Issues in the Controversy Regarding Foster Children in the Pediatric HIV/AIDS Clinical Trials

TitleManufacturing Mistrust: Issues in the Controversy Regarding Foster Children in the Pediatric HIV/AIDS Clinical Trials
Publication TypeJournal Article
Year of Publication2009
AuthorsSlomka, J
JournalScience & Engineering Ethics
Date Published12/2009
Type of ArticleArticle
Publication Languageeng
ISSN Number13533452
Accession Number45471927
Keywords(Disease) , aids , and , children , children; , Clinical , communication; , DISEASES , ethics , ETHICS; , FOSTER , HIV/AIDS , HIV/AIDS; , Human Research Subjects , in , media , Medical , MEDICINE , PEDIATRIC , professional , research , SUSPICION; , trials; , VIRUS , Vulnerable Populations
AbstractThe author discusses the ethical issues raised in the use use of foster children as subjects in the pediatric HIV/AIDS clinical trials, and discusses the unsettled issues and debates in research ethics underlying this controversy, and the lack of consensus among professional researchers about these issues. These include the tension between protecting subjects from research risk while allowing them access to the possible benefits of research, the the adequacy of Institutional Review Board oversight, and trust and the relationships among physicians, investigators and industry. The author sees the media controversy about the pediatric HIV/AIDS clinical trials as a means of “manufacturing mistrust” in health care, research and social services that have not always met the needs and expectations of the public, and calls on investigators, journalists and the public to become knowledgeable about major ethical issues in the conduct of research in order to engage in dialogue about balancing research risks and benefits and to be able to distinguish fact from distortion in an era of multiple and rapid transmission of information.
NotesSlomka, Jacquelyn 1; Email Address:; Affiliation: 1: Division of Health Promotion and Behavioral Sciences, School of Public Health, UCT 2530, The University of Texas Health Science Center at Houston, 1200 Herman Pressler, Houston, TX 77030, USA; Source Info: Dec2009, Vol. 15 Issue 4, p503; Subject Term: SUSPICION; Subject Term: FOSTER children; Subject Term: AIDS (Disease) in children; Subject Term: VIRUS diseases in children; Subject Term: CLINICAL trials; Subject Term: PROFESSIONAL ethics; Subject Term: MEDICAL ethics; Author-Supplied Keyword: Foster children and HIV/AIDS; Author-Supplied Keyword: Media and communication; Author-Supplied Keyword: Pediatric HIV/AIDS clinical trials; Author-Supplied Keyword: Research ethics; Number of Pages: 14p; Document Type: Article
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