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Date Approved:Undated
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GUIDING PRINCIPLES IN THE CARE AND USE OF ANIMALS
Approved by the Council of The American Physiological Society

Only animals that are lawfully acquired shall be used in laboratory, and their retention and use shall be in every case in compliance with federal, state and local laws and regulations

Animals in the laboratory must receive every consideration for their bodily comfort; they must be kindly treated, properly fed, and their surroundings kept in sanitary conditions.

Appropriate anesthetics must be used to eliminate sensibility to pain during operative procedures. Where recovery from anesthesia is necessary during the study, acceptable technic minimize pain must be followed. Curarizing agents are not anesthetics. Where the study does not require recovery from anesthesia the animal must be killed in a humane manner at the conclusion of the observations.

The postoperative care of animals shall be such as to minimize discomfort and pain, and in any case shall be equivalent to accepted practices of Veterinary Medicine.

When animals are used by students for their education or the advancements of science such work shall be under the direct supervision of an experienced teacher or investigator. The rules for the care of such animals must be the same for animals used or research.

The American Physiological Society endorses the Recommendations for the Declaration of Helsinki and the Guiding Principles in the Care and Use of Animals and insists which all investigations involving man and animal experimentation reported in its publications be conducted in conformity with these principles. Editors/Associate Editors are expected to refuse papers in that evidence of the adherence to these principles is not apparent. Differences of opinion will be adjudicated by the Publications Committee.

 
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