Toxicological Studies

Authors: Barnard, Amanda S.
Publication Type: Journal Article
Secondary Title: Nature Materials
Abstract: Because the possible hazards associated with nanomaterials are significant, the author calls on scientists to expand the scope of their research and increasing the diversity of their subject matter. Through focused research on disco...
Year: 2006
DOI: 10.1038/nmat1615

Authors: Medina, C ; Santos-Martinez, M J ; Radomski, A ; Corrigan, O I ; Radomski, M W
Publication Type: Journal Article
Secondary Title: British journal of pharmacology
Abstract: Article reviews current developments in the use of nanoparticles in pharmacology and therapeutics, the classes of nanoparticles being used, and the demonstrated and potential toxicity of these nanoparticles. ...
Year: 2007
DOI: 10.1038/sj.bjp.0707130

Authors: Service, R. F.
Publication Type: Journal Article
Secondary Title: Science
Abstract: Academic institutions, environmental groups, industry representatives, and government agencies are calling for a dramatic increase in funding to study and the possible negative effects nanotechnology might have on human health and t...
Year: 2005
DOI: 10.1126/science.310.5754.1609

Authors: Curtis, John ; Greenberg, Michael ; Kester, Janet ; Phillips, Scott ; Krieger, Gary
Publication Type: Journal Article
Secondary Title: Toxicological reviews
Abstract: Article gives an overview on the current level of knowledge of the potential toxicological effects of nanotechnology. While literature on this subject is limited, inhalational toxicity is to be expected based on what is known of the...
Year: 2006

Biblio - csep - 07/12/2010 - 14:42

Authors: Oberdörster, Günter ; Oberdörster, Eva ; Oberdörster, Jan
Publication Type: Journal Article
Secondary Title: Environmental health perspectives
Abstract: Although humans have been exposed to airborne nanosized particles for many years, the. he rapidly developing field of nanotechnology is likely increase this exposure through inhalation, ingestion, skin uptake, and injection of engin...
Year: 2005
URL: http://www.google.com/url?sa=t&source=web&cd=1&ved=0CBcQFjAA&url=http%3A%2F%2Fehp03.niehs.nih.gov%2Farticle%2FfetchArticle.action%3FarticleURI%3Dinfo%3Adoi%2F10.1289%2Fehp.7339&ei=9bVJTPWPIZjrnQfT4fHiDQ&usg=AFQjCNEvX-21byMIhAkmIOcmnji_p248cw

Authors: Nyland, J. ; Silbergeld, E.
Publication Type: Journal Article
Secondary Title: Human & Experimental Toxicology
Abstract: There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard to...
Year: 2009
DOI: 10.1177/0960327109105161

Authors: Service, Robert F.
Publication Type: Journal Article
Secondary Title: Science
Abstract: Studies done in New Orleans suggest that single-walled carbon nanotubes (SWNETs), tubes of graphite that have the potential to be used in nanoscale electronics and lightweight materials, may cause lesions in the lungs of mice. Curre...
Year: 2003
DOI: 10.1126/science.300.5617.243a

Authors: Nalwa, Hari Singh ; Singh, Surya
Publication Type: Journal Article
Secondary Title: Journal of Nanoscience and Nanotechnology
Abstract: This article summarizes some of the sources of various nanostructured materials, such as fullerenes and quantum dots, associated possible routes of human exposure, their biocompatibility in relation to their potential toxicological ...
Year: 2007
DOI: 10.1166/jnn.2007.922

Authors: K Donaldson ; V Stones . T Fernandez ; A Ford ; Institute of Occupational Medicine ; N Christofi ; JG Ayres ; M Steiner ; JF Hurley ; Tran, C.L. ; Aitken, R.J. ; A Seaton ; United Kingdom ; Health and Safety Executive
Publication Type: Report
Abstract: This study examines methodologies for examining the toxicology, ecotoxicology, persistence and bioaccumulation potential for manufactured unfixed nanoparticles and nanotubes, the differences in hazard posed by variations in nanopart...
Year: 2005
URL: http://www.defra.gov.uk/ENVIRONMENT/nanotech/research/pdf/hazarddata-scoping.pdf

Authors: Hardman, Ron
Publication Type: Journal Article
Secondary Title: Environmental Health Perspectives
Abstract: This article reviews some studies that have been done on the potential toxicity of quantum dots. Quantum dots are semiconductor nanocrystals with unique optical and electrical properties that are often currently used in biomedical i...
Year: 2006

Biblio - csep - 07/30/2010 - 15:42

Authors: New York Times
Publication Type: Newspaper Article
Secondary Title: New York Times
Abstract: Policy makers and investors are finding that it could require years of research to learn the potential environmental and health impacts of nanotechnology. Because the field is in its infancy and is growing rapidly, new questions abo...
Year: 2003

Biblio - csep - 08/03/2010 - 15:37

Authors: Maynard, Andrew D ; Robert J. Aitken
Publication Type: Journal Article
Secondary Title: Nanotoxicology
Abstract: The authors of this article explore the idea of building a new way of monitoring exposure to nanomaterials. This system would involve classifying airborne nanometer-scale particles and nano-meter structured particles based on their ...
Year: 2007

Biblio - csep - 08/03/2010 - 15:42

Authors: Parks, Noreen
Publication Type: Web Article
Secondary Title: ScienceNow: Daily News
Abstract: Little is know about the biological effect of engineered nanoparticles, yet more and more of them are being released into the environment. A study of nanoparticles of titanium dioxide found in personal care and food products, and us...
Year: 2006
URL: http://sciencenow.sciencemag.org/cgi/content/full/2006/615/1

Authors: Weiss, Rick
Publication Type: Newspaper Article
Secondary Title: Washington Post
Abstract: Study of the toxicity of buckyballs on bacteria in soil at Perdue University revealed that they had no discernible impact. Earlier studies had shown that they can kill soil bacteria in laboratory dishes, a fact which raised concerns...
Year: 2007
URL: http://www.washingtonpost.com/wp-dyn/content/article/2007/04/01/AR2007040100643_2.html?sub=new

Authors: Monteiro-Riviere, Nancy ; Yang, Hong ; Lai, David ; Warheit, David ; Kreyling, Wolfgang ; Karn, Barbara ; Carter, Janet ; Olin, Stephen ; Ausman, Kevin ; Fitzpatrick, Julie ; Castranova, Vincent ; Donaldson, Ken ; Maynard, Andrew ; Oberdörster, Günter ; ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group
Publication Type: Journal Article
Secondary Title: Particle and fibre toxicology
Abstract: Article conveying the recommendations of an expert working group convened by the International Life Sciences Institute Research Foundation/Risk Science Institute to develop a screening strategy for the hazard identification of engin...
Year: 2005
URL: http://www.particleandfibretoxicology.com/content/2/1/8

Authors: Parks, Noreen
Publication Type: Journal Article
Abstract: Little is know about the biological effect of engineered nanoparticles, yet more and more of them are being released into the environment. A study of nanoparticles of titanium dioxide found in personal care and food products, and us...
Year: 2006
URL: http://sciencenow.sciencemag.org/cgi/content/full/2006/615/1

Authors: Powers, Kevin ; Brown, Scott C. ; Krishna, Vijay B. ; Wasdo, Scott C. ; Moudgil, Brij M. ; Roberts, Stephen M.
Publication Type: Journal Article
Secondary Title: Toxicological Sciences
Abstract: This article discusses the need for developing a series of guidelines or recommended practices for the basic characterization of nanomaterials. These recommended practices should be developed jointly by physical scientists skilled i...
Year: 2006
DOI: 10.1093/toxsci/kfj099

Authors: Borm, Paul ; Klaessig, Frederick C. ; Landry, Timothy D. ; Moudgil, Brij ; Pauluhn, Jurgen ; Thomas, Karluss ; Trottier, Remi ; Wood, Stewart
Publication Type: Journal Article
Secondary Title: Toxicological Sciences
Abstract: Dissolution, translocation, and disposition have been shown to play a key role in the fate and effects of inhaled particles and fibers. Concepts that have been applied in the micron size range may be usefully applied to the nanoscal...
Year: 2006
DOI: 10.1093/toxsci/kfj084

Authors: Toxiikos Pty. Ltd.
Publication Type: Report
Abstract: This review reports the current understanding of the toxicology and health hazards associated with engineered nanomaterials, and the implications in regard to health hazards in occupational settings (i.e. during manufacture, handlin...
Year: 2009
URL: http://www.safeworkaustralia.gov.au/swa/AboutUs/Publications/Engineerednanomaterials-Areviewofthetoxicologyandhealthhazards.htm

Authors: Kagan, V.E. ; Shvedova, A. A.
Publication Type: Journal Article
Secondary Title: Journal of Internal Medicine
Abstract: This review discusses several important issues relevant to the pulmonary toxicity of nanoparticles, especially singled walled carbon nanotubes, their direct cytotoxic effect, their ability to cause an inflammatory response, and indu...
Year: 2010
DOI: 10.1111/j.1365-2796.2009.02188.x

Authors: Murphy, Catherine J. ; Alkilany, Alaaldin M.
Publication Type: Journal Article
Secondary Title: Journal of Nanoparticle Research
Abstract: Discusses recent research studies looking at the toxicity of gold nanoparticles both in vivo and in vitro, and provides some experimental recommendations for future research and the interface of nanotechnology and biological systems...
Year: 2010
DOI: 10.1007/s11051-010-9911-8

Authors: Oberdorster, Eva ; Kreyling, Wolfgang ; Stone, Vicki ; Schins, Roel ; Donaldson, Ken ; Warheit, David ; Fissan, Heinz ; Kuhlbusch, Thomas ; Krutmann, Jean ; Haubold, Stephan ; Robbins, David ; Lademann, Jurgen ; Borm, Paul J. A.
Publication Type: Journal Article
Secondary Title: Particle and Fibre Toxicology
Abstract: This review of a number of international reports on the possible toxicity of nanomaterials shows that (1) nanoparticles can deposit in the respiratory tract after inhalation, possibly crossing into the brain, (2) while there is litt...
Year: 2006
URL: http://www.particleandfibretoxicology.com/content/3/1/11
DOI: 10.1186/1743-8977-3-11

Authors: Oberdörster, G.
Publication Type: Journal Article
Secondary Title: Journal of Internal Medicine
Abstract: This article discusses the difficulty of accessing the toxicity of engineered nanoparticles, and points out that studies that use only extraordinary high doses must be interpreted with caution. The author discusses key concepts of n...
Year: 2010
DOI: 10.1111/j.1365-2796.2009.02187.x

Authors: Choi, Jae-Young ; Kandlikar, Milind ; Gurumurthy Ramachandran
Publication Type: Journal Article
Secondary Title: Environmental Science & Technology
Abstract: This paper analyzes the impact of testing costs on the United State's regulatory agencies' ability to gather information about nanoparticle toxicity and whether such costs could be reasonably be borne by an emerging industry. The ar...
Year: 2009
URL: http://pubs.acs.org/doi/abs/10.1021/es802388s
DOI: 10.1021/es802388s

Authors: Talbot, David
Publication Type: Web Article
Secondary Title: Technology Review
Abstract: Blog entry by the editor of Technology Review. Author remarks on the lack of any reported negative consequences of the use of nanoparticle containing products compared to the large amount of concern many scholars and environmental g...
Year: 2006
URL: http://www.technologyreview.com/blog/posts.aspx?id=17430