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Toxicity of an engineered nanoparticle (fullerene, C60) in two aquatic species, Daphnia and fathead minnow.
| Title | Toxicity of an engineered nanoparticle (fullerene, C60) in two aquatic species, Daphnia and fathead minnow. |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Zhu, Shiqian, Oberdörster Eva, and Haasch Mary L. |
| Journal | Marine environmental research |
| Volume | 62 Suppl |
| Pagination | S5-9 |
| Date Published | 07/2006 |
| ISSN Number | 0141-1136 |
| Abstract | The current study investigates differences in acute toxicity to Daphnia magna between THF-solubilized and water-stirred-nC60 as a range-find for further assays in adult male fathead minnow (FHM, Pimephales promelas). The daphnia 48-h LC50 for THF-nC60 was at least one order of magnitude less (0.8 ppm) than that for water-stirred-nC60 (> 35 ppm). FHM were dosed with either 0.5 ppm of THF- or water-stirred-nC60 for 48 h. There was 100% mortality in the THF-nC60-exposed fish between 6 and 18 h, while the water-stirred-nC60-exposed fish showed no obvious physical effects after 48 h. Water-stirred-nC60 elevated LPO in brain, significantly increased LPO in gill, and significantly increased expression of CYP2 family isozymes in liver as compared to control fish. |
| DOI | 10.1016/j.marenvres.2006.04.059 |
| Source Web Site | |
| Alternate Journal | Mar. Environ. Res. |