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Toxicity of an engineered nanoparticle (fullerene, C60) in two aquatic species, Daphnia and fathead minnow.


By csep - Posted on 11 June 2010

TitleToxicity of an engineered nanoparticle (fullerene, C60) in two aquatic species, Daphnia and fathead minnow.
Publication TypeJournal Article
Year of Publication2006
AuthorsZhu, Shiqian, Oberdörster Eva, and Haasch Mary L.
JournalMarine environmental research
Volume62 Suppl
PaginationS5-9
Date Published07/2006
ISSN Number0141-1136
Abstract

The current study investigates differences in acute toxicity to Daphnia magna between THF-solubilized and water-stirred-nC60 as a range-find for further assays in adult male fathead minnow (FHM, Pimephales promelas). The daphnia 48-h LC50 for THF-nC60 was at least one order of magnitude less (0.8 ppm) than that for water-stirred-nC60 (> 35 ppm). FHM were dosed with either 0.5 ppm of THF- or water-stirred-nC60 for 48 h. There was 100% mortality in the THF-nC60-exposed fish between 6 and 18 h, while the water-stirred-nC60-exposed fish showed no obvious physical effects after 48 h. Water-stirred-nC60 elevated LPO in brain, significantly increased LPO in gill, and significantly increased expression of CYP2 family isozymes in liver as compared to control fish.

DOI10.1016/j.marenvres.2006.04.059
Source Web Site

http://www.ncbi.nlm.nih.gov/pubmed/16709433?dopt=Abstract

Alternate JournalMar. Environ. Res.