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Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass.


By csep - Posted on 11 June 2010

TitleManufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass.
Publication TypeJournal Article
Year of Publication2004
AuthorsOberdörster, Eva
JournalEnvironmental health perspectives
Volume112
Issue10
Pagination1058-62
Date Published2004 Jul
Publication LanguageEnglish
ISSN Number0091-6765
Abstract

Although nanotechnology has vast potential in uses, it is important to determine possible toxicity of nanoparticle-containing products before widespread use. It is likely that nanomaterials can affect wildlife, water sources, and the environment if they are if they are accidentally released. One nanoparticle, fullerenes are being produced by tons each year, may cause damage to aquatic wildlife. This article summarizes the first study showing that uncoated fullerenes can cause oxidative damage and depletion of GSH in vivo in an aquatic species. Further research needs to be done to evaluate the potential toxicity of manufactured nanomaterials, especially with respect to translocation into the brain.

URLhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1247377/?tool=pubmed
DOI10.1289/ehp.7021
Source Web Site

http://www.ncbi.nlm.nih.gov/pubmed/15238277?dopt=Abstract

Alternate JournalEnviron. Health Perspect.